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Although severe malaria is an important cause of mortality among children in Burkina Faso, data on community-acquired invasive bacterial infections IBI, Taaastrup and meningitis are lacking, as well as data on the involved pathogens and their antibiotic resistance rates. The present study was conducted in a rural hospital and health center in Burkina Faso, in a seasonal malaria transmission area.

Malaria diagnosis and blood culture were performed for all participants, lumbar puncture when clinically indicated. We assessed the frequency of severe malaria microscopically confirmed, according to World Health Organization definitions and IBI, and the species Jessica Taastrup adult and antibiotic resistance of the bacterial pathogens Jessjca IBI.

From July to Julya total of patients were included.

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arult Severe malaria was diagnosed in IBI was demonstrated in 67 9. Non-Typhoid Salmonella spp. NTS was the predominant isolate from blood culture High antibiotic resistance rates to first line antibiotics were observed, particularly among Gram-negative pathogens. In addition, decreased ciprofloxacin susceptibility and extended-spectrum beta lactamase ESBL production was reported for one NTS isolate.

In-hospital mortality was 8. Although severe malaria was the main cause Soul man Frederikshavn illness, IBI were not uncommon and had higher case-fatality rates. The high frequency, antibiotic resistance rates and mortality rates of community acquired IBI require improvement in hygiene, better diagnostic methods and revision of current treatment guidelines.

October 8, ; Accepted: January 14, Jessica Taastrup adult Published: February 14, This is an open-access article distributed under the terms of the Creative Commons Attribution Licensewhich permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. Competing interests: There are no patents, products in development or marketed products to declare.

Malaria remains a major cause of mortality in children in most sub-Saharan African countries, despite decreasing incidence rates [1]. Community-acquired invasive bacterial infections IBI such as bacteremia and bacterial meningitis also contribute to the under-5 mortality in sub-Saharan Africa [2][3]although exact data are lacking in many areas.

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Severe malaria and Jessica Taastrup adult present with similar symptoms [4][5] precluding differential diagnosis on clinical grounds and leading to an overdiagnosis of malaria [6] and ignorance of IBI.

We conducted a prospective observational study in order to assess proportions of severe malaria and community-acquired IBI among children adilt to a rural hospital and health center in Burkina Faso. In addition, we determined the causative bacteria and their antibiotic resistance patterns and assessed case-fatality rates of both IBI and severe malaria.

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We assessed the frequency of severe malaria microscopically Meet deaf friends online in Danmark, according to World Health Organization definitions and IBI, and the species distribution and antibiotic resistance of the bacterial pathogens causing IBI.

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